CELL-DEATH - SHADOW BAXING

Authors
Citation
J. Silke et Dl. Vaux, CELL-DEATH - SHADOW BAXING, Current biology, 8(15), 1998, pp. 528-531
Citations number
22
Categorie Soggetti
Biology,Biology
Journal title
ISSN journal
09609822
Volume
8
Issue
15
Year of publication
1998
Pages
528 - 531
Database
ISI
SICI code
0960-9822(1998)8:15<528:>2.0.ZU;2-N
Abstract
Bcl-2, one of a family of key regulators of apoptosis, was the first c ell-death machinery component to be Identified, but how the family fun ctions is still not clear. Mammalian Bar, a pro-apoptotic family membe r, can cause yeast cells to die, and two recent yeast genetic screens shed light: on how Bar might function.