EFFECTS OF GLUTATHIONE DEPLETORS ON POSTISCHEMIC REPERFUSION IN RAT-BRAIN

Authors
MARTINEZ G CARNAZZA ML CAMPISI A SORRENTI V DIGIACOMO C PEREZPOLO JR VANELLA A
Citation
G. Martinez et al., EFFECTS OF GLUTATHIONE DEPLETORS ON POSTISCHEMIC REPERFUSION IN RAT-BRAIN, Neurochemical research, 23(7), 1998, pp. 961-968
Citations number
24
Categorie Soggetti
Biology,Neurosciences
Journal title
Neurochemical research → ACNP
ISSN journal
03643190
Volume
23
Issue
7
Year of publication
1998
Pages
961 - 968
Database
ISI
SICI code
0364-3190(1998)23:7<961:EOGDOP>2.0.ZU;2-Q
Abstract
The present paper reports the effects of GSH depletion (diethylmaleate induced) on partial cerebral ischemia and reperfusion for 7 and 20 da ys. Our results confirm that there is a paradoxical protective effect of the GSH-depletor and suggest an improved neuronal trophism induced by diethylmaleate treatment.