INHIBITORS OF THE BACTERIAL-CELL WALL BIOSYNTHESIS ENZYME MURD

Authors
GEGNAS LD WADDELL ST CHABIN RM REDDY S WONG KK
Citation
Ld. Gegnas et al., INHIBITORS OF THE BACTERIAL-CELL WALL BIOSYNTHESIS ENZYME MURD, Bioorganic & medicinal chemistry letters, 8(13), 1998, pp. 1643-1648
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
13
Year of publication
1998
Pages
1643 - 1648
Database
ISI
SICI code
0960-894X(1998)8:13<1643:IOTBWB>2.0.ZU;2-1
Abstract
A series of transition-state analog inhibitors of the D-glutamic acid- adding enzyme (MurD) of bacterial peptidoglycan biosynthesis has been synthesized and evaluated for inhibition of the E. coli enzyme. (C) 19 98 Elsevier Science Ltd. All rights reserved.