COMPARATIVE GENOMIC HYBRIDIZATION - TECHNICAL DEVELOPMENT AND CYTOGENETIC ASPECTS FOR ROUTINE USE IN CLINICAL LABORATORIES (VOL 41, PG 56, 1998)

Authors
LAPIERRE JM CACHEUX V DASILVA F COLLOT N HERVY N WISS J TACHEDJIAN G
Citation
Jm. Lapierre et al., COMPARATIVE GENOMIC HYBRIDIZATION - TECHNICAL DEVELOPMENT AND CYTOGENETIC ASPECTS FOR ROUTINE USE IN CLINICAL LABORATORIES (VOL 41, PG 56, 1998), Annales de genetique, 41(2), 1998, pp. 87-88
Citations number
1
Categorie Soggetti
Genetics & Heredity
Journal title
Annales de genetique → ACNP
ISSN journal
00033995
Volume
41
Issue
2
Year of publication
1998
Pages
87 - 88
Database
ISI
SICI code
0003-3995(1998)41:2<87:CGH-TD>2.0.ZU;2-W
Abstract
Comparative genomic hybridization (CGH) offers a new global approach f or detection of chromosomal material imbalances of the entire genome i n a single experiment without cell culture; In this paper,.we discuss the technical development and the cytogenetic aspects of CGH in a clin ical laboratory. Based only on the visual inspection of CGH metaphase spreads, the correct identification of numerical.and structural anomal ies are reported.No commercial image analysis software was required in these experiments. We have demonstrated that this new technology can bie set up easily for routine use in a clinical:cytogenetics laborator y.