Craniofacial deformities of 14 patients with amniotic band syndrome at
one institution were reviewed for morphologic similarities. In additi
on to associated cleft lip and palate, vertical and oblique facial cle
fts, which were not associated with embryologic lines of fusion, were
seen. It is hypothesized that the prominence of the nasal processes co
mbined with the adjacent stomodeal orifice results in utero surfaces,
which can lead to free band attachment and adherence, resulting in a s
pectrum of similarly oriented facial defects.