INCOMPLETE LACUNAR INFARCTION (TYPE IB LACUNES)

Citation
Ga. Lammie et al., INCOMPLETE LACUNAR INFARCTION (TYPE IB LACUNES), Acta Neuropathologica, 96(2), 1998, pp. 163-171
Citations number
38
Categorie Soggetti
Neurosciences,"Clinical Neurology",Pathology
Journal title
ISSN journal
00016322
Volume
96
Issue
2
Year of publication
1998
Pages
163 - 171
Database
ISI
SICI code
0001-6322(1998)96:2<163:ILI(IL>2.0.ZU;2-Y
Abstract
The aetiopathogenesis of small, deep (lacunar) infarcts remains contro versial. The view that they are caused by occlusive intrinsic small ve ssel disease is widely held, but is based on only a small number of de tailed pathology studies. We describe and illustrate a variant of smal l, microvessel-associated basal ganglia lesion, the histopathological features of which are distinct from those of classical Types I, II and III lacunes. Their appearances suggest a state of incomplete infarcti on. The pathogenetic significance of such lesions is discussed, in par ticular the role of mechanisms causing temporary or only moderately se vere ischaemia.