GROWTH IN CHILDHOOD AND BLOOD-PRESSURE IN FINNISH CHILDREN

The aims of this prospective cohort study were to monitor childhood bl ood pressure (BP) and cholesterol and link them to fetal and childhood growth. Of the 215 children recruited after delivery in a rural count y of eastern Finland during 1981 and 1982, 180 (83.7%) stayed in the s tudy until the age of seven. The measurements assessed were BP, serum cholesterol and anthropometry. Of the children originally in the highe st BP quartile at the age of 6 months, 58% (systolic BP (SBP)) and 68% (diastolic BP (DBP)), respectively, remained in the same quartile unt il the age of 7 years; 53% (SBP) and 60% (DBP), respectively, remained in the same lowest quartile. Consequently, BP at 6 months correlated strongly with SEP (r = 0.69, P < 0.001) and DBP (r = 0.75, P < 0.001) at 7 years of age. Birth weight, ponderal index, placental weight and placental to birth weight ratio were not related to BP level during th e follow-up. Weight at I year of age correlated positively with SEP (r = 0.18-0.25, P = 0.0008-0.0215) but not with DBP during the follow-up . Weight gain during the first year of life was directly related to su bsequent SEP (r = 0.11-0.22, P = 0.005-0.16). There was an inverse rel ationship between serum cholesterol at 7 years of age and placental we ight (r = -0.16, P = 0.048) and placental to birth weight ratio (r = - 0.16, P = 0.045). The BP level is already determined at 1 year of age and a higher SEP is associated with a higher growth rate during the fi rst year of life.