DEVELOPMENT AND CHARACTERIZATION OF AN INTEGRATED ON-CAPILLARY TUBULAR ELECTRODE FOR CAPILLARY ELECTROPHORESIS ELECTROCHEMISTRY/

An integrated on-capillary electrochemical detector for capillary elec trophoresis is described. It consists of a gold tube permanently fixed onto the end of a capillary. This detector configuration eliminates t he need for micromanipulators for electrode alignment. The large surfa ce area of the gold tubular electrode results in better sensitivity fo r PAD detection than is attainable with a gold wire electrode. Applica tion of this detector to the determination of glucose in serum by CE-P AD is described.