CYCLIC VOLTAMMETRY DETERMINATION OF EPINEPHRINE WITH A CARBON-FIBER ULTRAMICROELECTRODE

A carbon fiber ultramicroelectrode was used for the electroanalytical determination of epinephrine in biological fluids (urine) by cyclic vo ltammetry. The ultramicroelectrode was subjected to an electrochemical pretreatment in order to improve the epinephrine adsorption on the el ectrode surface. With this preconcentration step, detection limits of 7.8 ng ml(-1) and determination limits of 27.6 ng ml(-1) can be reache d. The method was contrasted with native fluorescence determination - similar results were obtained. (C) 1998 Elsevier Science B.V. All righ ts reserved.