ISOSTRUCTURAL METABOLITES OF 2 ANTI-PARKINSON DRUGS

Authors
SIMON K HARMAT V TOROK Z BOCSKEI Z HERMECZ I
Citation
K. Simon et al., ISOSTRUCTURAL METABOLITES OF 2 ANTI-PARKINSON DRUGS, Acta crystallographica. Section C, Crystal structure communications, 54, 1998, pp. 811-813
Citations number
15
Categorie Soggetti
Crystallography
Journal title
Acta crystallographica. Section C, Crystal structure communications → ACNP
ISSN journal
01082701
Volume
54
Year of publication
1998
Part
6
Pages
811 - 813
Database
ISI
SICI code
0108-2701(1998)54:<811:IMO2AD>2.0.ZU;2-D
Abstract
The absolute configurations of desmethylselegiline hydrochloride [(R)- (-)-1-benzyl-N-(2-propynyl)ethylammonium chloride, C12H16N+.Cl-], (1), and p-fluorodesmethylselegiline hydrochloride (-)-1-(4-fluorobenzyl)- N-(2-propynyl)ethylammonium chloride, C12H15FN+.Cl-], (2), have been d etermined. The two compounds are metabolites of the anti-Parkinson age nt selegiline and its backup, p-fluoroselegiline. The two crystal stru ctures are highly isostructural.