Twister theory shows that deformations of a hypercomplex manifold corr
espond to deformations of a canonically constructed holomorphic map fr
om the twister space of the hypercomplex manifold onto the complex pro
jective line. Applying Horikawa's theory of deformations of maps, eve
calculate deformations of compact quotients and twists of the associat
ed bundles of quaternionic manifolds. In particular, deformations of h
ypercomplex structures on Stiefel manifolds are discussed.