Objective: To employ standardized techniques to measure and characteri
ze the pain associated with leg ulcers of defined causes. Methods: Pat
ients attending leg ulcer clinics were interviewed by one research nur
se using a structured questionnaire. Ulcers were classified as venous,
arterial or mixed depending on the clinical assessment and ankle-brac
hial systolic pressure index. Pain was assessed objectively using two
validated instruments for scoring pain: a verbal rating scale and a pa
in-intensity visual analogue scale. The significance of the observatio
ns was tested using either the Mann-Whitney U-test (unpaired observati
ons) or the Wilcoxon signed-rank test (paired observations). A profile
of the quality of pain was obtained using the short-form McGill Pain
Questionnaire (SF-MPQ). Quality of life was assessed using the COOP Ch
art System. Patients: We assessed 38 patients with venous ulcers, thre
e patients with mixed arterial/venous ulceration and 10 patients with
arterial disease. Main outcome measures: Pain scores on verbal rating
scales and visual analogue scales. Results: Venous leg ulcers are pain
ful. Although pain scores are greater in arterial ulcers, most patient
s with venous ulceration suffer at least moderate pain. Night pain dis
turbed sleep in 73% of all patients and pain affected mood in more tha
n 50%. Dressing changes exacerbated pain. Conclusions: Pain reduces th
e quality of life in most patients with leg ulcers. Pain control is an
essential consideration in all patients with leg ulcers.