GAS-CHROMATOGRAPHY IN THE LOW CONCENTRATION DETERMINATION OF NITROUS-OXIDE AND VOLATILE ANESTHETICS

A previously reported single-column gas chromatographic separation met hod was modified for dual detection gas chromatography (TCD + FID) and evaluated for the low concentration analysis of volatile anaesthetics (halothane, isoflurane) and nitrous oxide. It was found that no serio us problem occurs in the determination of volatile anaesthetics with F ID (<10 ppm), but nitrous oxide introduces lack of sensitivity at lowe r concentrations with TCD (<40 ppm) in the described analysis method w ith a 0.25 mi sample loop.