SYNTHESIS OF THE SESQUITERPENOID TRICHODIENE USING A FREE-RADICAL FRAGMENTATION APPROACH

Authors
LANGE GL FURLAN L MACKINNON MC
Citation
Gl. Lange et al., SYNTHESIS OF THE SESQUITERPENOID TRICHODIENE USING A FREE-RADICAL FRAGMENTATION APPROACH, Tetrahedron letters, 39(31), 1998, pp. 5489-5492
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
31
Year of publication
1998
Pages
5489 - 5492
Database
ISI
SICI code
0040-4039(1998)39:31<5489:SOTSTU>2.0.ZU;2-4
Abstract
A highly regio- and stereoselective synthesis of the sesquiterpenoid t richodiene is reported. The approach requires only nine steps starting with a [2+2] photoaddition and employs the free radical fragmentation of an ''external'' cyclobutane bond in a key step. (C) 1998 Elsevier Science Ltd. All rights reserved.