FUNCTIONALIZATION OF SOLID SUPPORTS WITH N-UNPROTECTED DEOXYRIBONUCLEOSIDES

Authors
WADA T MOCHIZUKI A SATO Y SEKINE M
Citation
T. Wada et al., FUNCTIONALIZATION OF SOLID SUPPORTS WITH N-UNPROTECTED DEOXYRIBONUCLEOSIDES, Tetrahedron letters, 39(31), 1998, pp. 5593-5596
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
31
Year of publication
1998
Pages
5593 - 5596
Database
ISI
SICI code
0040-4039(1998)39:31<5593:FOSSWN>2.0.ZU;2-1
Abstract
N-Unprotected deoxyribonucleotides were loaded to solid supports via a succinyl or an oxalyl linker. These solid supports were successfully used for oligonucleotide synthesis by the H-phosphonate method without N-protecting groups. (C) 1998 Elsevier Science Ltd. All rights reserv ed.