A LARGE-SCALE AND CONCISE SYNTHESIS OF GAMMA-LINOLENIC ACID FROM 4-CHLOROBUT-2-YN-1-OL

Authors
DURAND S PARRAIN JL SANTELLI M
Citation
S. Durand et al., A LARGE-SCALE AND CONCISE SYNTHESIS OF GAMMA-LINOLENIC ACID FROM 4-CHLOROBUT-2-YN-1-OL, Synthesis, (7), 1998, pp. 1015-1018
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
7
Year of publication
1998
Pages
1015 - 1018
Database
ISI
SICI code
0039-7881(1998):7<1015:ALACSO>2.0.ZU;2-1
Abstract
A large scale and concise synthesis of gamma-linolenic acid is describ ed. They key step of the synthesis involves a copper salt mediated cro ss-coupling of two different alkynes and chlorobutynol.