PURPOSE: To prospectively evaluate the efficacy and safety of emergenc
y selective arterial embolization in the management of intractable pri
mary postpartum hemorrhage. MATERIALS AND METHODS: Twenty-seven consec
utively seen women with life-threatening primary postpartum hemorrhage
underwent uterine embolization. In all cases, hemostatic embolization
was performed because of intractable hemorrhage that could not be con
trolled with vaginal packing and administration of uterotonic drugs. T
he mean hemoglobin level before embolization was 7.48 g/dL +/- 2.39 (7
4.8 g/L +/- 23.9) (1 standard deviation). Hysterectomy performed in tw
o patients before embolization failed to stop the bleeding. RESULTS: A
ngiography revealed extravasation in nine patients arid spasm of the b
ranches the internal iliac artery in five. The procedure consisted of
embolization of uterine (n = 46), vaginal (n = 5), or ovarian(n = 2) a
rteries or anterior division of internal iliac arteries (n = 8). Immed
iate disappearance or dramatic diminution of external bleeding was obs
erved in all cases. Two patients needed repeated embolization the next
day. No major complication related to embolization was found.ln one p
atient with placenta accreta, delayed hysterectomy was necessary. Norm
al menstruation resumed in all women except the two who underwent hyst
erectomy. One woman became pregnant after embolization. CONCLUSION: Em
ergency arterial embolization is a safe and effective means of control
of primary postpartum hemorrhage. The procedure obviates high-risk su
rgery and allows maintenance of reproductive ability.