FUNCTIONAL BRAIN IMAGING OF HUMAN SLEEP

Citation
P. Maquet et C. Phillips, FUNCTIONAL BRAIN IMAGING OF HUMAN SLEEP, Journal of sleep research, 7, 1998, pp. 42-47
Citations number
34
Categorie Soggetti
Neurosciences,"Behavioral Sciences",Physiology
Journal title
ISSN journal
09621105
Volume
7
Year of publication
1998
Supplement
1
Pages
42 - 47
Database
ISI
SICI code
0962-1105(1998)7:<42:FBIOHS>2.0.ZU;2-6
Abstract
This paper presents an overview of the contribution of functional brai n mapping to the study of human sleep, Early studies were essentially successful in describing the variations of the global level of cerebra l metabolism. More recently, regional distribution of cerebral blood f low was reported. The results suggest that the permissive and executiv e processes of slow wave sleep and REM sleep are similar in humans and in animals. They also show cortical blood flow distributions specific to each sleep stage. The cellular mechanisms underlying the involveme nt of these cortical areas in sleep are not yet precisely known. They should be looked for by further investigations in animals. Future rese arch in functional neuroimaging will attempt to explore functional and , hopefully, effective connectivity between cerebral areas involved in sleep processes. This final goal will probably require the co-registr ation of two or more brain imaging techniques to precisely describe th e spatio-temporal course of neuronal interactions occurring during sle ep.