A NEW HPLC ANALYTICAL METHOD TO STUDY FUNGAL CAFFEINE METABOLISM

Citation
S. Denis et al., A NEW HPLC ANALYTICAL METHOD TO STUDY FUNGAL CAFFEINE METABOLISM, Biotechnology techniques, 12(5), 1998, pp. 359-362
Citations number
16
Categorie Soggetti
Biothechnology & Applied Migrobiology","Biochemical Research Methods
Journal title
ISSN journal
0951208X
Volume
12
Issue
5
Year of publication
1998
Pages
359 - 362
Database
ISI
SICI code
0951-208X(1998)12:5<359:ANHAMT>2.0.ZU;2-4
Abstract
A simple and rapid HPLC method has been developed to analyse all the m ethylxanthines that can be produced by N-demethylation of 1,3,7-trimet hylxanthine (caffeine). This method is particularly suitable to study caffeine metabolism of a filamentous fungus (Aspergillus sp V12A25) cu ltivated in a synthetic liquid medium containing caffeine as the sole source of nitrogen.