We report four cases of Merkel cell carcinoma, a rare cutaneous neuroe
ndocrine neoplasm with a high malignant potencial. The first patient i
s a 90 year old male presenting with a tumor in the left superior eyel
id. Surgical excision was the only treatment and seven months later; a
local and regional tumoral relapse caused the death of this patient.
The second patient is a 83 years old female with a tumor in her left e
ar She was treated surgically and with radiotherapy, being free of dis
ease after years of follow up. The third patient is a 45 years old mal
e with a tumor in the left forearm. Treatment was surgical excision of
the primary tumor and axillary lymph nodes. He received post operativ
e radiotherapy and is free of disease after three years of follow up.
The last case is a 76 years old male, who was subjected only to an exc
isional biopsy of a lesion located in the left knee. He had a tumor re
lapse with inguinal and crural lymph node involvement that caused his
death 12 months later.