Cyclospora cayetanensis is a newly recognized parasite widely distribu
ted throughout the world, and isolated from children, immunocompetent
adults and HIV infected individuals. The clinical manifestations of th
e infection are watery prolonged diarrhea, anorexia, fatigue, nausea,
bloating and weight loss. In immunocompetent individuals, diarrhea is
usually self limited but may last several weeks. In immunocompromised
hosts it is prolonged, severe and can be associated with biliary tract
involvement. We report a 50 years old female that, five days after re
turning from Cuba, presented with low grade fever; anorexia, fatigue,
explosive diarrhea and weight loss. Physical examination was normal. A
stool specimen contained many organisms with morphological features o
f Cyclospora caetanensis. The diagnosis was confirmed at the Centers f
or Disease Control (Atlanta Ga).