SELECTIVE N-ALKYLATION OF PYRROLOPYRIMIDINES AND INDOLES BY TRANSFER OF ACTIVATION

Authors
SOBOLOV SB SUN JM COOPER BA
Citation
Sb. Sobolov et al., SELECTIVE N-ALKYLATION OF PYRROLOPYRIMIDINES AND INDOLES BY TRANSFER OF ACTIVATION, Tetrahedron letters, 39(32), 1998, pp. 5685-5688
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
32
Year of publication
1998
Pages
5685 - 5688
Database
ISI
SICI code
0040-4039(1998)39:32<5685:SNOPAI>2.0.ZU;2-1
Abstract
The benzene sulfonyl group is used as a ''transfer of activation'' rea gent to alkylate selectively the NH of both pyrrolopyrimidines and 5-a minoindoles substituted on thienopyrimidines. A variety of primary and secondary alcohols are utilized as alkylating substrates. (C) 1998 El sevier Science Ltd. Ail rights reserved.