CHIRAL PHOSPHINOOXAZOLINES WITH A BI-CYCLIC OR TRICYCLIC OXAZOLINE MOIETY - APPLICATIONS IN PD-CATALYZED ALLYLIC ALKYLATIONS

Authors
WIESE B HELMCHEN G
Citation
B. Wiese et G. Helmchen, CHIRAL PHOSPHINOOXAZOLINES WITH A BI-CYCLIC OR TRICYCLIC OXAZOLINE MOIETY - APPLICATIONS IN PD-CATALYZED ALLYLIC ALKYLATIONS, Tetrahedron letters, 39(32), 1998, pp. 5727-5730
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
32
Year of publication
1998
Pages
5727 - 5730
Database
ISI
SICI code
0040-4039(1998)39:32<5727:CPWABO>2.0.ZU;2-7
Abstract
Phosphinooxazolines with a bi- or tricyclic oxazoline moiety are descr ibed. In Pd-catalyzed alkylations of 1.3-dimethylallyl acetate with so dium dimethyl malonate enantiomeric excess of up to 89.5 % was obtaine d. This is the best result so far achieved for this substrate with P,N -chelate ligands. (C) 1998 Elsevier Science Ltd. AII rights reserved.