NOVEL AND GENERAL ENTRY INTO PSEUDOGUAIANOLIDES - FORMAL AND ENANTIOSELECTIVE SYNTHESIS OF (-CONFERTIN())

Authors
OHTSUKA M TAKEKAWA Y SHISHIDO K
Citation
M. Ohtsuka et al., NOVEL AND GENERAL ENTRY INTO PSEUDOGUAIANOLIDES - FORMAL AND ENANTIOSELECTIVE SYNTHESIS OF (-CONFERTIN()), Tetrahedron letters, 39(32), 1998, pp. 5803-5806
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
32
Year of publication
1998
Pages
5803 - 5806
Database
ISI
SICI code
0040-4039(1998)39:32<5803:NAGEIP>2.0.ZU;2-7
Abstract
A novel and general access to pseudoguaianolide sesquiterpenoids has b een developed by employing a diastereoselective acyl radical-mediated 7-endo-trigonal mode of cyclization as a key reaction step. The method ology has successfully been applied to the formal enantioselective syn thesis of (+)-confertin. (C) 1998 Elsevier Science Ltd. All rights res erved.