THE USE OF AQUEOUS DIMETHYLAMINE AS REAGENT FOR THE REGIOSPECIFIC C4-EPIMERIZATION OF CIS-3-SUBSTITUTED 4-FORMYL-2-AZETIDINONES

Authors
ALCAIDE B ALY MF RODRIGUEZVICENTE A
Citation
B. Alcaide et al., THE USE OF AQUEOUS DIMETHYLAMINE AS REAGENT FOR THE REGIOSPECIFIC C4-EPIMERIZATION OF CIS-3-SUBSTITUTED 4-FORMYL-2-AZETIDINONES, Tetrahedron letters, 39(32), 1998, pp. 5865-5866
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
32
Year of publication
1998
Pages
5865 - 5866
Database
ISI
SICI code
0040-4039(1998)39:32<5865:TUOADA>2.0.ZU;2-C
Abstract
A simple and efficient method for the synthesis of trans-3-substituted 4-formyl-2-azetidinones 2 is described based on the regiospecific C4- epimerization of the cis-isomers 1 using aqueous dimethylamine as reag ent in heterogeneous medium. (C) 1998 Elsevier Science Ltd. All rights reserved.