CARRIER-FACILITATED LIQUID MEMBRANE EXTRACTION OF PENICILLIN-G FROM AQUEOUS STREAMS

Kinetics and mechanism for the carrier-facilitated transport of penici llin G from aqueous solutions through a supported liquid membrane cont aining Amberlite LA-2 were investigated. The strip phase was either ph osphate buffer or sodium carbonate solution. Experiments were performe d as a function of the pH, the concentrations of penicillin G in the f eed phase and of amine in the membrane phase. A transport model was pr oposed considering aqueous film diffusion, interfacial chemical reacti on, and membrane diffusion. The calculated rates were found to agree w ith the measured ones (average standard error, 12%). Under the conditi ons investigated (feed pH 5.02-7.83, penicillin G concentration 10-500 mol/m(3), amine concentration 50-1000 mol/m(3)), the present transpor t process was shown to be governed by combined interfacial chemical re action and membrane diffusion. (C) 1998 Elsevier Science B.V. All righ ts reserved.