ADVANCES IN MULTIMODALITY THERAPY FOR LARYNGEAL CANCER

Combined induction chemotherapy and external beam radiation therapy is an effective treatment for selected patients with advanced-stage lary ngeal cancer. The larynx can be preserved in two-thirds of patients re ceiving this treatment. Investigations continue to evaluate the ideal treatment regimen, the delivery of chemotherapy, patient selection, bi ologic markers predicting response, functional outcome, and the effect iveness of this treatment at other sites.