A. Winthernielsen et al., POSTERIOR CAPSULE OPACIFICATION AND NEODYMIUM-YAG CAPSULOTOMY WITH HEPARIN-SURFACE-MODIFIED INTRAOCULAR LENSES, Journal of cataract and refractive surgery, 24(7), 1998, pp. 940-944
Purpose: To compare the effect of heparin-surface-modified (HSM) and c
onventional unmodified poly(methyl methacrylate) (PMMA) intraocular le
nses (IOLs) on the formation posterior capsule opacification (PCO). Se
tting: Department of Ophthalmology, Vejle Hospital Denmark. Methods: T
his prospective, randomized, double-blind study comprised 250 eyes of
246 patients who had uneventful extracapsular cataract extraction in o
therwise healthy eyes with implantation of a biconvex IOL or a convex-
piano lens with a continuous laser ridge. Patients were examined once
a year for 3 years, at which time the degree of PCO was recorded. A ne
odymium:YAG laser capsulotomy was performed if certain criteria were m
et. Results: The incidence of PCO was statistically significantly high
er in eyes with an HSM convex-plano laser-ridge IOL than in those with
an unmodified convex-plano lens (P < .005). There were no significant
differences between any other groups. Conclusion: The incidence of PC
O was higher in eyes with an HSM convex-plano IOL with a laser ridge.