Im. Lazar et al., CAPILLARY ELECTROPHORESIS-TIME-OF-FLIGHT MASS-SPECTROMETRY OF DRUGS OF ABUSE, Analyst (London. 1877. Print), 123(7), 1998, pp. 1449-1454
The use of capillary electrophoresis (CE) for the determination of dru
gs of abuse was explored. A commercial CE system was interfaced with a
laboratory-built time-of-flight mass spectrometer (TOFMS) which was e
quipped with a high-speed data acquisition system to provide accurate
monitoring of efficient separations. Ionization of the CE eluent was a
chieved with an electrospray ionization source. Standard mixtures and
seized samples were analyzed either by direct infusion of the analyte
solutions or after separation by CE. Detection at the low femtomole le
vel was obtained using CE-TOFMS.