USE OF CAPILLARY-ELECTROPHORESIS AS A METHOD DEVELOPMENT TOOL FOR CLASSICAL GEL-ELECTROPHORESIS

Capillary electrophoresis (CE) was used to optimize the buffer pH, ion ic strength and sulfated cyclodextrin concentrations for enantiomeric separation of piperoxan. These enantioseparation conditions were then applied to a classical gel electrophoresis system. Binding constants o f the sulfated beta-cyclodextrin-piperoxan couple mere approximated us ing CE and the effects of organic solvents on the system were also inv estigated.