Bacteremia occurs frequently among critically ill patients. The aim of
this study carried out in Eastern France was to describe the epidemio
logy of nosocomial bacteremia and to assess the methicillin-resistance
of Staphylococcus aureus (SA), Data were collected during a 4 months
prospective survey (09/96-12/96) carried out among 44 hospitals. We co
unted 2633 episodes of bacteremia classified as contamination (684), n
osocomial bacteremia (970) and community bacteremia (979). Incidence r
ate of nosocomial bacteremia was 30,7 per 100 beds in the intensive ca
re units. When documented, the origin of the nosocomial bacteremia was
the most often catheter blood related infection or urinary tract infe
ction. Gram positif cocci were predominant among nosocomial bacteremia
(53,8 %). Among Gram negative bacteria (enterobacteria) (31,6 %), Esc
herichia coli was the most frequently isolated. SA was methicillin-res
istant in 18,3 % of community bacteremia and in 26,5 % of nosocomial b
acteremia. Coagulase negative Staphylococcus were methicillin-resistan
t in 25,4 % of community bacteremia and in 60,1 % of nosocomial bacter
emia. Measures to prevent catheter blood related infections and urinar
y tract infections may be started.