Infections associated with central catheters are a significant source
of morbidity in cancer patients. The first evaluation done as part of
a continuous catheter surveillance program included the 913 central ca
theters inserted in 1995, Three of these catheters are still in place.
All were tunneled subcutaneously, and most were inserted via the subc
lavian route. There were 839 simple silicone catheters and 74 catheter
s with a cuff. Two groups were defined based on whether the central ca
theter was inserted for administering inpatient or outpatient chemothe
rapy (n = 704) or for another reason (perioperative care, symptomatic
or palliative therapy; n = 209). Catheter-related infection was define
d as an infection at the catheter site or as septicemia retrospectivel
y shown to be related to the catheter. The risk of catheter-related in
fection was expressed as the number of cases per 1000 days of catheter
ization. Reasons for catheter removal were distributed in table I.