D. Umeno et al., SINGLE-STRANDED DNA-POLY(N-ISOPROPYLACRYLAMIDE) CONJUGATE FOR AFFINITY PRECIPITATION SEPARATION OF OLIGONUCLEOTIDES, Chemical communications, (14), 1998, pp. 1433-1434
The conjugate between single-stranded DNA and the temperature-responsi
ve polymer poly(N-isopropylacrylamide) was synthesized, and was demons
trated to distinguish its target sequence from mismatch DNAs and separ
ate it from aqueous solution when heated.