Jo. Schorge et al., POSTPARTUM AND VULVAR NECROTIZING FASCIITIS - EARLY CLINICAL-DIAGNOSIS AND HISTOPATHOLOGIC CORRELATION, Journal of reproductive medicine, 43(7), 1998, pp. 586-590
OBJECTIVE: To review the clinical course and correlate histopathologic
findings of obstetrics and gynecology patients with necrotizing fasci
itis. STUDY DESIGN: Seventeen patients with postpartum or vulvar necro
tizing fasciitis were identified from 1981 to 1996. Medical records we
re retrospectively reviewed. Information was available for all patient
s until death or discharge from the hospital. Histopathologic material
on 15 patients was available for review. RESULTS: Five postpartum pat
ients were diagnosed and surgically debrided one to nine days after ce
sarean delivery, with no mortality. Twelve patients with vulvar necrot
izing fasciitis were diagnosed and surgically debrided <1-10 days afte
r presentation to a physician, with three deaths (25%). On histopathol
ogic review, all crises had prominent lobular and septal panniculitis.
Thirteen cases had histologic evidence of fasciitis. CONCLUSION: Earl
y diagnosis and aggressive surgical debridement in patients with postp
artum and vulvar necrotizing fasciitis may improve the outcome. Histop
athologic findings are remarkably consistent and may help to confirm t
he diagnosis.