F. Liu et al., INHIBITION OF EXTRACELLULAR PROTEASE SECRETION BY ASPERGILLUS-NIGER USING CELL IMMOBILIZATION, Biotechnology letters, 20(6), 1998, pp. 539-542
A wild-type A. niger strain was employed as a model to investigate the
effect of cell immobilization on extracellular protease secretion dur
ing fermentation. A metal-coated pad of polyester latex felt was used
to immobilize the cells in shake flasks. Compared with free suspension
culture, the maximum specific activity of the extracellular protease
from immobilized cells was reduced from 129 units/g to 28 units/g.