The maximum O-2 uptake by Rhizopus oligosporus grown in a 200 litre ro
tating drum bioreactor at 0.5 rpm ranged from 6.7 to 7.6 mmol per min
per kg initial dry substrate (IDS), for runs done with 4 baffles each
17 cm wide, and 12 baffles each 5 cm wide. Without baffles, the maximu
m O-2 uptake rate at 5 rpm was 6.9 mmol/(min.kg IDS), compared to 5.1
mmol/(min.kg IDS) obtained at 0.5 rpm. Therefore O-2 supply is adequat
e in rotating drum bioreactors as long as slumping flow regimes of the
substrate bed are avoided.