THE IGF SYSTEM DURING FETAL-PLACENTAL DEVELOPMENT OF THE MOUSE

Authors
VANKLEFFENS M GROFFEN C LINDENBERGHKORTLEVE DJ VANNECK JW GONZALEZPARRA S DITS N ZWARTHOFF EC DROP SLS
Citation
M. Vankleffens et al., THE IGF SYSTEM DURING FETAL-PLACENTAL DEVELOPMENT OF THE MOUSE, Molecular and cellular endocrinology, 140(1-2), 1998, pp. 129-136
Citations number
54
Categorie Soggetti
Endocrynology & Metabolism","Cell Biology
Journal title
Molecular and cellular endocrinology → ACNP
ISSN journal
03037207
Volume
140
Issue
1-2
Year of publication
1998
Pages
129 - 136
Database
ISI
SICI code
0303-7207(1998)140:1-2<129:TISDFD>2.0.ZU;2-6
Abstract
Insulin-like growth factors (IGF-I and -II) promote cellular mitosis a nd differentiation and have been implicated in fetal and placental gro wth. Together with the IGF receptors and IGF binding proteins (IGFBPs) they form a complex network, with tissue specific activity. This revi ew will discuss the data generated to elucidate the functions of the I GF system during mouse development. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.