OBJECTIVE. The aim of this paper is to clarify the clinical and radiol
ogic features of sternocostoclavicular hyperostosis by reviewing eight
previously unpublished cases in children, identifying its similaritie
s to chronic recurrent multifocal osteomyelitis and the differences be
tween the pediatric and adult population affected with sternocostoclav
icular hyperostosis. Appropriate imaging workup will obviate unnecessa
ry diagnostic and therapeutic procedures. MATERIALS AND METHODS. We in
vestigated the clinical and imaging features of sternocostoclavicular
hyperostosis in eight children (seven girls and one boy) and compared
those features with the characteristic features of chronic recurrent m
ultifocal osteomyelitis and sclerosing Garre's osteomyelitis to determ
ine if sternocostoclavicular hyperostosis can justifiably be classifie
d as a separate entity. All patients underwent one or more bone biopsi
es to determine the cause of the bone lesion(s). RESULTS. Seven of the
eight patients had involvement of the clavicle, Five of the eight pat
ients had associated distant involvement in the pelvis, femur, tibia,
fibula, talus, or sacroiliac joints. Except for predominant localizati
on in the anterior chest wall, the symptoms, the clinical and imaging
features, and the results of biopsy and histopathologic examination re
semble those of chronic recurrent nonspecific sclerosing osteomyelitis
, No skin lesion and no causative organism was found in any of the cas
es. CONCLUSION. Sternocostoclavicular hyperostosis is a descriptive te
rm used to designate a form of chronic sclerosing osteomyelitis. Its o
nly distinctive feature is localization on one or more sites of the an
terior chest wall.