SURGICAL-MANAGEMENT OF MITRAL REGURGITATION ASSOCIATED WITH MARFANS-SYNDROME

Background. The surgical treatment of mitral regurgitation associated with Marfan's syndrome remains controversial because of the underlying degenerative process. Methods. From October 1986 to June 1996, 33 pat ients with Marfan's syndrome underwent a mitral valve procedure. The m ean age was 30 years (range, 2 to 55 years). Mitral regurgitation was caused by annulus dilatation in 2 patients, leaflet prolapse in 30 pat ients, and restricted leaflet motion in 1 patient. Mitral valve repair was performed in all patients except 1 who had mitral valve replaceme nt, Results, Two patients died in the perioperative period. All surviv ors were available for follow-up, which ranged from 1 month to 122 mon ths (mean follow-up, 39 months). There were three late deaths, two of which were related to aortic complications. The actuarial survival rat e was 78.9% at 10 years. Freedom from mitral valve reoperation was 87, 1% at 10 years. Echocardiographic studies were obtained in all survivo rs and showed absent or mild (1+) mitral regurgitation in 21 patients and moderate (2+) mitral regurgitation in 3. Conclusions. Mitral valve repair for mitral regurgitation in patients with Marfan's syndrome ca n be performed safely in almost all instances. This technique provided stable midterm results comparable with those obtained for other degen erative mitral valve diseases. (Ann Thorac Surg 1998;66:68-72) (C) 199 8 by The Society of Thoracic Surgeons.