DEVELOPMENT OF NEW CHROMANOL ANTAGONISTS OF LEUKOTRIENE D-4

Authors
CHAMBERS RJ ANTOGNOLI GW CHENG JB MARFAT A PILLAR JS SHIRLEY JT WATSON JW
Citation
Rj. Chambers et al., DEVELOPMENT OF NEW CHROMANOL ANTAGONISTS OF LEUKOTRIENE D-4, Bioorganic & medicinal chemistry letters, 8(14), 1998, pp. 1791-1796
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
14
Year of publication
1998
Pages
1791 - 1796
Database
ISI
SICI code
0960-894X(1998)8:14<1791:DONCAO>2.0.ZU;2-C
Abstract
By addressing the issues of potency and metabolism in 3, a new series of LTD, antagonists represented by (+)-26 was developed which is equip otent to clinical LTD, antagonists Zafirlukast (1) and Pranlukast (2). (C) 1998 Elsevier Science Ltd. All rights reserved.