INHIBITION OF LIPID-PEROXIDATION MEDIATED BY INDOLIZINES

Authors
NASIR AI GUNDERSEN LL RISE F ANTONSEN O KRISTENSEN T LANGHELLE B BAST A CUSTERS I HAENEN GRMM WIKSTROM H
Citation
Ai. Nasir et al., INHIBITION OF LIPID-PEROXIDATION MEDIATED BY INDOLIZINES, Bioorganic & medicinal chemistry letters, 8(14), 1998, pp. 1829-1832
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
14
Year of publication
1998
Pages
1829 - 1832
Database
ISI
SICI code
0960-894X(1998)8:14<1829:IOLMBI>2.0.ZU;2-8
Abstract
Esters, ethers, carbonates and carbamates of 1-indolizinols and azaind olizinols exhibit a profound inhibition of lipid peroxidation in vitro . The antioxidants were prepared by cyclization of pyridines and diazi nes with diphenylcyclopropenone followed by introduction of the O-subs tituent. (C) 1998 Elsevier Science Ltd. All rights reserved.