[H-3]LY341495, A HIGHLY POTENT, SELECTIVE AND NOVEL RADIOLIGAND FOR LABELING GROUP-II METABOTROPIC GLUTAMATE RECEPTORS

Authors
ORNSTEIN PL ARNOLD MB BLEISCH TJ WRIGHT RA WHEELER WJ SCHOEPP DD
Citation
Pl. Ornstein et al., [H-3]LY341495, A HIGHLY POTENT, SELECTIVE AND NOVEL RADIOLIGAND FOR LABELING GROUP-II METABOTROPIC GLUTAMATE RECEPTORS, Bioorganic & medicinal chemistry letters, 8(14), 1998, pp. 1919-1922
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
14
Year of publication
1998
Pages
1919 - 1922
Database
ISI
SICI code
0960-894X(1998)8:14<1919:[AHPSA>2.0.ZU;2-Z
Abstract
We report herein the synthesis and pharmacological characterization of a tritiated version of the potent and selective cyclopropyl amino aci d LY341495 as a radioligand to label group II metabotropic glutamate r eceptors in rat brain homogenates. (C) 1998 Elsevier Science Ltd. All rights reserved.