Y. Fukusima et al., ENZYMATIC-SYNTHESIS OF CARBOCYCLIC ANALOG OF FRUCTOSE 2,6-BISPHOSPHATE WITH 6-PHOSPHOFRUCTO-2-KINASE, Chemistry Letters, (7), 1998, pp. 575-576
cF26P2 was synthesized enzymatically by the regioselective phosphoryla
tion of cF6P with PFK2 and ATP, cF26P2 was found to be much stabler in
the acidic condition than F26P2 and could activate the glycolytic pat
hway enzyme PFK.