Da. Regier et al., PREVALENCE OF ANXIETY DISORDERS AND THEIR COMORBIDITY WITH MOOD AND ADDICTIVE DISORDERS, British Journal of Psychiatry, 173, 1998, pp. 24-28
Background The co-occurrence of anxiety disorders with other mental, a
ddictive, and physical disorders has important implications for treatm
ent and for prediction of clinical course and associated morbidity. Me
thod Cross-sectional and prospective data on 20 291 individuals from t
he Epidemiologic Catchment Area (ECA) study were analysed to determine
one-month, current disorders. one-year incidence, and one-year and li
fetime prevalence of anxiety, mood, and addictive disorders, and to id
entify the onset and offset of disorders within the one-year prospecti
ve period. Results Nearly half (47.2%) of those meeting lifetime crite
ria for major depression also have met criteria for a comorbid anxiety
disorder.The average age of onset. of any lifetime anxiety disorder (
16.4 years) and social phobia (11.6 years) among those with major depr
ession was much younger than the onset age for major depression (23.2
years) and panic disorder. Conclusions Anxiety disorders, especially s
ocial and simple phobias, appear to have an early onset in adolescence
with potentially severe consequences. predisposing those affected to
greater vulnerability to major depression and addictive disorders.