Calciphylaxis represents a rare complication of end-stage renal diseas
e with hyperparathyroidism. We report the case of a 26-year-old woman
with systemic calciphylaxis secondary to chronic renal failure who dev
eloped mitral annular calcification and a right middle cerebral artery
stroke. The high-density lesion seen on CT scan of the brain probably
represents a calcified cerebral embolus originating from the mitral v
alve.