Aims-To evaluate the diagnostic yield and safety of a new push type vi
deoenteroscope (PVE) for diagnosis of small bowel disease. Methods-Thr
ee hundred and thirteen patients were referred for one or two way PVE
from December 1993 to June 1996. Indications for PVE were: an unexplai
ned iron deficiency anaemia with or without clinically evident gastroi
ntestinal bleeding; or a complementary investigation for suspected sma
ll bowel disease, after a small bowel barium follow through (SBBFT) co
nsidered as normal or abnormal, but without a definite diagnosis. Resu
lts-A jejunoscopy and a retrograde ileoscopy were carried our in 306 a
nd 234 patients, respectively. In patients with isolated anaemia (n=13
1) and those with clinically evident gastrointestinal bleeding associa
ted anaemia (n=72), PVE provided a diagnosis in 26 (19.8%) and 22 (30.
5%) cases, respectively. Lesions found were located in the jejunoileum
in 30 (14.7%) patients and in the gastroduodenum or the colon in 18 (
8.8%) patients-that is, within the reach oft he conventional gastrosco
pe/ colonoscope. In patients with normal (n=54) or abnormal (n=56) SBB
FT, PVE provided a diagnosis in 17 (31%) and 27 (48%) cases, respectiv
ely. In 25% of cases, the abnormal appearance of SBBFT was not confirm
ed. The site of the radiological abnormality was not reached in 27% of
cases. Lesions were located at the jejunum and the ileum in 59 (64%)
and 33 (36%) cases, respectively. Conclusions-PVE is useful in around
30% of cases of unexplained anaemia or after an SBBFT which failed to
provide an accurate aetiological diagnosis. Use of retrograde videoent
eroscopy increases diagnostic yield by one third.