Aims-To determine the sources of funding for UK gastroenterology resea
rch papers and the relative impact of papers funded by different group
s and of unfunded ones. Methods-UK gastroenterology papers from 1985-9
4 were selectively retrieved from the Science Citation Index by means
of a specially constructed filter based on their title keywords and jo
urnal names. They were looked up in libraries to determine their fundi
ng sources and these, together with their numbers of authors, numbers
of addresses, and research category (clinical/basic) were considered a
s input parameters to the research. Output parameters analysed were me
an journal impact category, citation counts by papers, and the frequen
cy of citation by a US patent. Results-Gastroenterology papers compris
e about 7% of all UK biomedical research and 46% of them have no ackno
wledged funding source. One quarter of the papers acknowledged governm
ent support, and a similar fraction a private, non-profit source; 11%
were funded by the pharmaceutical industry The papers acknowledging fu
nding had significantly more impact than the others on all three measu
res. The citing patents had six times more UK inventors than the avera
ge for all US Patent and Trademark Office patents in the relevant clas
ses and were mostly generic in application. Conclusion-The variation i
n impact of papers funded by different sources can mostly be explained
by a simple model based on the input factors (numbers of funding bodi
es, numbers of authors, numbers of addresses, and research type). The
national science base in gastroenterology is important for the underpi
nning of UK invented patents citing to it.