L. Galzigna et al., A SYNTHETIC CALCIUM-CHELATING L-GLUTAMYL-L-SERINE PHOSPHATE (GLU-SER.P) ENHANCES CALCIUM-ABSORPTION IN THE RAT, The journal of peptide research, 52(1), 1998, pp. 15-18
A new synthetic procedure was used to prepare L-glutamyl-L-serine phos
phate (Glu-Ser.P) with a good yield. The phosphopeptide is able to che
late calcium ion as shown by conductimetric titration and through the
use of a calcium-specific electrode. Intestinal absorption of radioact
ive calcium is enhanced in rats fed Ca-45 and Glu-Ser.P.