Objective-To evaluate the risk of hepatitis A virus (HAV) infection am
ong sewage workers from occupational exposure to raw sewage. Methods-A
n analytical cross sectional study of 241 company employees with possi
ble occupational exposure to sewage in a large water and sewerage comp
any was carried out. Previous exposure to hepatitis A virus infection
was assessed, as were its associations with possible risk factors. Res
ults-Frequent occupational exposure to raw sewage was a significant ri
sk factor for HAV infection, independently of other known risk factors
(odds ratio 3.73, 95% confidence interval 1.48 to 9.37). Of 50 employ
ees who reported occupational exposure to raw sewage most of the time,
30 (60%) had had HAV infection. Conclusion-Employees who are likely t
o be at risk of frequent exposure should have their immunity ensured.
The salivary assay for IgG anti-HAV used in the study was highly speci
fic and would be suitable for prevaccination testing of older employee
s, who are more likely to be immune.