STEREOSELECTIVE SYNTHESIS OF HYDROXYLATED INDOLIZIDINES VIA (-)-SPARTEINE-MEDIATED KINETIC RESOLUTION COUPLED WITH INTRAMOLECULAR CARBOLITHIATION

Authors
WOLTERING MJ FROHLICH R WIBBELING B HOPPE D
Citation
Mj. Woltering et al., STEREOSELECTIVE SYNTHESIS OF HYDROXYLATED INDOLIZIDINES VIA (-)-SPARTEINE-MEDIATED KINETIC RESOLUTION COUPLED WITH INTRAMOLECULAR CARBOLITHIATION, Synlett, (7), 1998, pp. 797-800
Citations number
48
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
7
Year of publication
1998
Pages
797 - 800
Database
ISI
SICI code
0936-5214(1998):7<797:SSOHIV>2.0.ZU;2-U
Abstract
Enantioenriched 1-oxy-2-benzyl-substituted indolizidines with function alized side chains were easily prepared from racemic 2-(carbamoyloxy)m ethyl-N-cinnamylpiperidine by (-)-sparteine-mediated one-step kinetic resolution and intramolecular carbolithiation.